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Details of Prof. Dirk Snyders   


Gender male
Job title Professor
Department Biomedical Sciences
University of Antwerp (
Universiteitsplein 1 Antwerpen 2610
University of Antwerp Universiteitsplein 1
Tel +3232652335
Fax +3232652326
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Degree MD, PhD
Job type Research
Research Area(s) Marine Biotechnology, Marine Products , Marine Biotechnology, Marine Products
Research Activities Electrophysiology, patch clamp
Research Region n/a
Working languages English, Dutch, French
Skills/Expertise Bophysical analysis marine toxins
PUBLICATIONS (as reported by Prof. Dirk SNYDERS)

Kopljar I, Labro AJ, Cuypers E, Johnson RWB, Rainier JD, Tytgat J and Snyders DJ: A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol. Proc. Natl. Acad. Sci. 106:9896-9901, 2009
Vandendriessche T, Kopljar I, Jenkins DP, Diego-Garcia E, Abdel-Mottaleb Y, Vermassen E, Clynen E, Schoofs L, Wulff H, Snyders D, Tytgat J: Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): The first member of a new kappa-KTX subfamily. Biochem. Pharmacol. 83:1307-17, 2012
Cuypers E, Abdel-Mottaleb Y, Kopljar I, Rainier JD, Raes AL, Snyders DJ, Tytgat J: Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels. Toxicon 51:974-983, 2008
Kopljar I, Labro AJ, de Block T, Rainier JD, Tytgat J, Snyders DJ. The ciguatoxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state. J Gen Physiol 141:359-69, 2013

Created: 2014-09-08 Last Updated: 2016-06-29 by Dirk SNYDERS