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Details of Mr. Steve Peigneur   


PERSONAL DATA

Gender male
Job title Assistant
Department pharmaceutical Sciences
Institution
KU Leuven ( KUL)
Kasteelpark Arenberg 10 (PB2445) Heverlee 3001
Address
Herestraat 49, Box 922 O&N2
Leuven
3000
Tel +3216323407
Email
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Social Media Links
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PROFESSIONAL DATA

Degree MSci
Job type Research
Research Area(s) Marine Biotechnology, Marine Products , Marine Biotechnology, Marine Products
Research Activities marine based drug discovery by exploring the potential pharmacological tools in (the venom of)cone snails,sea anemones, sponges,fish,...
Research Region 102
Working languages English, French, Dutch
Skills/Expertise Toxinology Pharmacology drug discovery
PUBLICATIONS (as reported by Mr. Steve PEIGNEUR)

BcsTx3 is a founder of a novel sea anemone toxin family of potassium channel blocker. Orts DJ, Moran Y, Cologna CT, Peigneur S, Madio B, Praher D, Quinton L, De Pauw E, Bicudo JE, Tytgat J, de Freitas JC. FEBS J. 2013 Oct;280(19):4839-52. doi: 10.1111/febs.12456. Epub 2013 Aug 23. PMID: 23895459 [PubMed - indexed for MEDLINE] Related citations Select item 23764262 2. A novel sea anemone peptide that inhibits acid-sensing ion channels. Rodríguez AA, Salceda E, Garateix AG, Zaharenko AJ, Peigneur S, López O, Pons T, Richardson M, Díaz M, Hernández Y, Ständker L, Tytgat J, Soto E. Peptides. 2014 Mar;53:3-12. doi: 10.1016/j.peptides.2013.06.003. Epub 2013 Jun 10. PMID: 23764262 [PubMed - in process] Related citations Select item 23727489 3. The proteomic profile of Stichodactyla duerdeni secretion reveals the presence of a novel O-linked glycopeptide. Cassoli JS, Verano-Braga T, Oliveira JS, Montandon GG, Cologna CT, Peigneur S, Pimenta AM, Kjeldsen F, Roepstorff P, Tytgat J, de Lima ME. J Proteomics. 2013 Jul 11;87:89-102. doi: 10.1016/j.jprot.2013.05.022. Epub 2013 May 29. PMID: 23727489 [PubMed - indexed for MEDLINE] Related citations Select item 23466933 4. Biochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum. Orts DJ, Peigneur S, Madio B, Cassoli JS, Montandon GG, Pimenta AM, Bicudo JE, Freitas JC, Zaharenko AJ, Tytgat J. Mar Drugs. 2013 Mar 6;11(3):655-79. doi: 10.3390/md11030655. PMID: 23466933 [PubMed - indexed for MEDLINE] Free PMC Article Related citations Select item 22972919 5. A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins. Peigneur S, Béress L, Möller C, Marí F, Forssmann WG, Tytgat J. FASEB J. 2012 Dec;26(12):5141-51. doi: 10.1096/fj.12-218479. Epub 2012 Sep 12. PMID: 22972919 [PubMed - indexed for MEDLINE] Free Article Related citations Select item 22851925 6. Atypical reactive center Kunitz-type inhibitor from the sea anemone Heteractis crispa. Gladkikh I, Monastyrnaya M, Leychenko E, Zelepuga E, Chausova V, Isaeva M, Anastyuk S, Andreev Y, Peigneur S, Tytgat J, Kozlovkaya E. Mar Drugs. 2012 Jul;10(7):1545-65. doi: 10.3390/md10071545. Epub 2012 Jul 19. PMID: 22851925 [PubMed - indexed for MEDLINE] Free PMC Article Related citations Select item 24061123 7. TRPV1 Channel as New Target for Marine Toxins: Example of Gigantoxin I, a Sea Anemone Toxin Acting Via Modulation of the PLA2 Pathway. Cuypers E, Peigneur S, Debaveye S, Shiomi K, Tytgat J. Acta Chim Slov. 2011 Dec;58(4):735-41. PMID: 24061123 [PubMed] Related citations Select item 21477583 8. A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties. Peigneur S, Billen B, Derua R, Waelkens E, Debaveye S, Béress L, Tytgat J. Biochem Pharmacol. 2011 Jul 1;82(1):81-90. doi: 10.1016/j.bcp.2011.03.023. Epub 2011 Apr 6. Conotoxins targeting nicotinic acetylcholine receptors: an overview. Lebbe EK, Peigneur S, Wijesekara I, Tytgat J. Mar Drugs. 2014 May 22;12(5):2970-3004. doi: 10.3390/md12052970. PMID: 24857959 [PubMed - in process] Free PMC Article Related citations Select item 24671422 3. Structure-function elucidation of a new ?-conotoxin, Lo1a, from Conus longurionis. Lebbe EK, Peigneur S, Maiti M, Devi P, Ravichandran S, Lescrinier E, Ulens C, Waelkens E, D'Souza L, Herdewijn P, Tytgat J. J Biol Chem. 2014 Apr 4;289(14):9573-83. doi: 10.1074/jbc.M114.556175. Epub 2014 Feb 24. PMID: 24567324 [PubMed - indexed for MEDLINE] Related citations Select item 24055806 4. A 'conovenomic' analysis of the milked venom from the mollusk-hunting cone snail Conus textile--the pharmacological importance of post-translational modifications. Bergeron ZL, Chun JB, Baker MR, Sandall DW, Peigneur S, Yu PY, Thapa P, Milisen JW, Tytgat J, Livett BG, Bingham JP. Peptides. 2013 Nov;49:145-58. doi: 10.1016/j.peptides.2013.09.004. Epub 2013 Sep 18. PMID: 24055806 [PubMed - in process] Related citations Select item 23871692 5. Ala-7, His-10 and Arg-12 are crucial amino acids for activity of a synthetically engineered ?-conotoxin. Lebbe EK, Peigneur S, Brullot W, Verbiest T, Tytgat J. Peptides. 2014 Mar;53:300-6. doi: 10.1016/j.peptides.2013.07.005. Epub 2013 Jul 16. PMID: 23871692 [PubMed - in process] Related citations Select item 23764262 6. A novel sea anemone peptide that inhibits acid-sensing ion channels. Rodríguez AA, Salceda E, Garateix AG, Zaharenko AJ, Peigneur S, López O, Pons T, Richardson M, Díaz M, Hernández Y, Ständker L, Tytgat J, Soto E. Peptides. 2014 Mar;53:3-12. doi: 10.1016/j.peptides.2013.06.003. Epub 2013 Jun 10. PMID: 23764262 [PubMed - in process] Related citations Select item 23698359 7. Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors. Kendel Y, Melaun C, Kurz A, Nicke A, Peigneur S, Tytgat J, Wunder C, Mebs D, Kauferstein S. Toxins (Basel). 2013 May 21;5(5):1043-50. doi: 10.3390/toxins5051043. PMID: 23698359 [PubMed - indexed for MEDLINE] Free PMC Article Related citations Select item 23567999 8. Identification, structural and pharmacological characterization of ?-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor. Petrel C, Hocking HG, Reynaud M, Upert G, Favreau P, Biass D, Paolini-Bertrand M, Peigneur S, Tytgat J, Gilles N, Hartley O, Boelens R, Stocklin R, Servent D. Biochem Pharmacol. 2013 Jun 1;85(11):1663-71. doi: 10.1016/j.bcp.2013.03.019. Epub 2013 Apr 5. PMID: 23567999 [PubMed - indexed for MEDLINE] Related citations Select item 22776330 9. Unraveling the peptidome of the South African cone snails Conus pictus and Conus natalis. Peigneur S, Van Der Haegen A, Möller C, Waelkens E, Diego-García E, Marí F, Naudé R, Tytgat J. Peptides. 2013 Mar;41:8-16. doi: 10.1016/j.peptides.2012.07.002. Epub 2012 Jul 7. PMID: 22776330 [PubMed - indexed for MEDLINE] Related citations Select item 22773842 10. Design of bioactive peptides from naturally occurring ?-conotoxin structures. Stevens M, Peigneur S, Dyubankova N, Lescrinier E, Herdewijn P, Tytgat J. J Biol Chem. 2012 Sep 7;287(37):31382-92. doi: 10.1074/jbc.M112.375733. Epub 2012 Jul 6. PMID: 22773842 [PubMed - indexed for MEDLINE] Free PMC Article Related citations Select item 22084632 12. Pc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivity. Van Der Haegen A, Peigneur S, Dyubankova N, Möller C, Marí F, Diego-García E, Naudé R, Lescrinier E, Herdewijn P, Tytgat J. Peptides. 2012 Mar;34(1):106-13. doi: 10.1016/j.peptides.2011.10.026. Epub 2011 Nov 3. PMID: 22079220 [


Created: 2014-07-07 Last Updated: 2015-05-15 by Steve PEIGNEUR